Masterclass Computational Approaches and In Silico Enzyme Library Design for Applied Biocatalysis

The course aims to make participants familiar with the use of structural biology and computational tools for engineering the performance of enzymes that are relevant for applied biocatalysis and synthetic biology. The theoretical and practical parts are integrated in a few problem-solving modules. Participants will have the opportunity to share their research via short oral presentations, posters, and interactive lectures.Tutors and teachers:Dick Janssen, University of GroningenHein Wijma, University of GroningenAndy-Mark Thunnissen, University of GroningenJiri Damborsky, Masaryk University, BrnoDavid Bednar, Masaryk University, BrnoEmanule Monza, Zymvol, Barcelona(to be) invited:Rene de Jong, The NetherlandsTopics:Protein crystallography and structure analysisHomology modeling docking and molecular dynamics simulations (Yasara)Computational enzyme (re)design (Rosetta)Enzyme engineering supported by web toolsSequence and structure based smart librariesThermostability and stereoselectivity engineeringIndustrial examples of enzyme engineering.

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3rd Hands-on Computational Enzyme Design

Computational tools can dramatically accelerate the discovery and design of improved enzymes. This online course will introduce a number of user friendly web-based computational tools for redesigning enzyme properties and will provide intensive practical

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5th Advanced in silico Drug Design workshop/challenge

5ADD workshop/challenge (3.2.-7.2.2020) is focused on the use of in silico drug design tools and approaches in the drug design. We will cover both structure-based drug design (molecular docking, molecular dynamics, structural bioinformatics tools) and

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5th Hands-on Computational Enzyme Design Course

Computational tools can dramatically accelerate the discovery and design of improved enzymes. This online course will introduce a number of user-friendly web-based computational tools for redesigning enzyme properties and will provide intensive practical

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4th Hands-on Computational Enzyme Design

Computational tools can dramatically accelerate the discovery and design of improved enzymes. This hybrid in-person/online course will introduce a number of user-friendly web-based computational tools for redesigning enzyme properties and will provide int

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4th Advanced in silico Drug Design workshop/hackathon 2019

4ADD workshop/hackathon (21.1.-25.1.2019) is focused on the use of in silico drug design tools and approaches in the drug design and optimization. Workshop will cover both structure-based drug design (molecular docking, molecular dynamics, structural bioi

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