EnzymeMiner & SoluProt: mining of soluble enzymesJiří Hon from ICRCWe present two integrated bioinformatics tools EnzymeMiner and SoluProt for mining and rational selection of novel soluble enzymes. EnzymeMiner uses one or more enzyme sequences and a description of essential residues to find enzyme family members among millions of uncharacterized protein sequences in the NCBI nr database. SoluProt is a machine-learning method for prediction of soluble protein expression in E. coli integrated in EnzymeMiner for prioritization of search hits. EnzymeMiner and SoluProt help to identify novel putative enzymes and facilitate selection of several expressible targets for experimental characterization. These novel enzymes might have successful applications in biosynthetic pathways for the ecological production or degradation of chemical compounds.Meet us online every friday morning to explore the portfolio of ELIXIR CZ tools and services at https://global.gotomeeting.com/join/508817845 .Registration is not neededFuture webinars11. 6. at 9:30 IRESs, IRESite and HCVIVdb.18. 6. at 9:30 CaverDock: Analysis of Ligand Transport through Protein Tunnels.25. 6. at 9:30 PrankWeb.Take a look at the webinar and give us your feedback. Please note that online session will be recorded and may be used on ELIXIR CZ website, social media, in ELIXIR CZ e-publications and any other ELIXIR CZ online materials.
cpPredictor: template based prediction of RNA secondary structuresJosef Pánek from MBU Cpredict is an algorithm for template-based prediction of secondary structures of RNAs. As templates, experimentally identified RNA structures are used. Reliability of
projít na článekTraveler: visualization of secondary structure of RNA moleculesDavid Hoksza from UKTraveler is a tool for template-based visualization of RNA secondary structure. If a sufficiently close template is available, Traveler is able to generate a layout for eve
projít na článek2DProts: Family-wide 2D diagrams of protein secondary structureRadka Svobodová from MU2DProts database contains secondary structure 2D diagrams for proteins and protein domains. Moreover, it includes multiple 2D diagrams of protein familys secondary struc
projít na článekFireProt: Computational tool for the design of stable proteinsMiloš Musil from ICRC FireProt is a family of tools for the design and analysis of stable proteins. FireProt-web is a server for the fully automated design of stable multiple-point mutants, whi
projít na článekWe are sorry to inform you that due to ELIXIR CZ Annual Conference 2021 we need to skip a usual service introduction on Friday, 26 November. Join us for the conference, registration is open until 11 November, or have a look on our video library on YouTube
projít na článek